Science Publishing Group: American Journal of Pediatrics: Table of Contents
<i>American Journal of Pediatrics (AJP)</i> is a peer-reviewed, open-access journal featuring research articles of exceptional significance in all areas of pediatric medicines. It is published bimonthly in English-language, providing a broad coverage of internal medicine. <i>AJP</i> publishes papers as well as independently submitted clinical studies, editorials, reviews, brief reports, correspondence and book reviews. The journal provides a high-quality forum for pediatricians and other healthcare professionals to report and discuss up-to-the-minute researches and expert reviews in the field of pediatric medicine. The journal will continue to develop the range of articles published to enable this invaluable resource to stay at the forefront of the field.
http://www.sciencepublishinggroup.com/j/ajp Science Publishing Group: American Journal of Pediatrics: Table of Contents
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American Journal of Pediatrics
American Journal of Pediatrics
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Development of Pulmonary Hypertension in an Infant Treated With Diazoxide for Hyperinsulinism, a Case Report and Literature Review
http://www.sciencepublishinggroup.com/journal/paperinfo.aspx?journalid=380&doi=10.11648/j.ajp.20150101.11
Congenital hyperinsulinism (CHI) is heterogeneous disorder in the neonatal period characterized by inappropriate insulin secretion in the presence of hypoglycemia. Known etiologies include inactivating mutations of the KATP channel. Its management can be extremely complicated, and may involve medical therapy and surgery. We describe a full term baby male at one month-old without dysmorphic features or congenital anomalies, the baby was presented with asymptomatic hypoglycemia by routine screening at the age of 1.5 hour of life, he was treated with diazoxide for prolonged neonatal hyperinsulinism. Tolerance of diazoxide is usually excellent, but several adverse effects of this drug have been described. During diazoxide therapy he presented with tachycardia and low oxygen saturation, the baby became dyspnoeic with fluid retention and facial edema. Echocardiography showed moderate pulmonary hypertension. Diazoxide was withdrawn, his clinical status and pulmonary hypertension dramatically improved and returned to baseline.
Congenital hyperinsulinism (CHI) is heterogeneous disorder in the neonatal period characterized by inappropriate insulin secretion in the presence of hypoglycemia. Known etiologies include inactivating mutations of the KATP channel. Its management can be extremely complicated, and may involve medical therapy and surgery. We describe a full term baby male at one month-old without dysmorphic features or congenital anomalies, the baby was presented with asymptomatic hypoglycemia by routine screening at the age of 1.5 hour of life, he was treated with diazoxide for prolonged neonatal hyperinsulinism. Tolerance of diazoxide is usually excellent, but several adverse effects of this drug have been described. During diazoxide therapy he presented with tachycardia and low oxygen saturation, the baby became dyspnoeic with fluid retention and facial edema. Echocardiography showed moderate pulmonary hypertension. Diazoxide was withdrawn, his clinical status and pulmonary hypertension dramatically improved and returned to baseline.
Development of Pulmonary Hypertension in an Infant Treated With Diazoxide for Hyperinsulinism, a Case Report and Literature Review
doi:10.11648/j.ajp.20150101.11
American Journal of Pediatrics
2015-07-23
© Science Publishing Group
Albahri Ziad
Lukeš Antonín
Mynářová Kateřina
Krylová Kateřina
Al Mawiri Abdul
Hussain Khaled
Neumann David
Development of Pulmonary Hypertension in an Infant Treated With Diazoxide for Hyperinsulinism, a Case Report and Literature Review
1
1
3
3
2015-07-23
2015-07-23
10.11648/j.ajp.20150101.11
http://www.sciencepublishinggroup.com/journal/paperinfo.aspx?journalid=380&doi=10.11648/j.ajp.20150101.11
© Science Publishing Group
Giant Aplasia Cutis Congenita of the Scalp in a Newborn, Case Report
http://www.sciencepublishinggroup.com/journal/paperinfo.aspx?journalid=380&doi=10.11648/j.ajp.20150101.12
Aplasia cutis congenita is a rare disease of unknown etiology, usually affects the scalp, but any part of the body may be affected, full thickness loss is extremely rare. We report a case of a boy born with a large scalp and skull defect measuring 8*9 cm without associated anomalies. After 2 years follow up with conservative treatment, the patient now is without neurodeficit, with approximately healing of affected skine and small reduction of the bone defected size.
Aplasia cutis congenita is a rare disease of unknown etiology, usually affects the scalp, but any part of the body may be affected, full thickness loss is extremely rare. We report a case of a boy born with a large scalp and skull defect measuring 8*9 cm without associated anomalies. After 2 years follow up with conservative treatment, the patient now is without neurodeficit, with approximately healing of affected skine and small reduction of the bone defected size.
Giant Aplasia Cutis Congenita of the Scalp in a Newborn, Case Report
doi:10.11648/j.ajp.20150101.12
American Journal of Pediatrics
2015-07-23
© Science Publishing Group
Albahri Z.
Krylová, K.
Al Mawiri A.
Bartoňová J.
Štefáčková Š.
Dočekalová Š.
Giant Aplasia Cutis Congenita of the Scalp in a Newborn, Case Report
1
1
5
5
2015-07-23
2015-07-23
10.11648/j.ajp.20150101.12
http://www.sciencepublishinggroup.com/journal/paperinfo.aspx?journalid=380&doi=10.11648/j.ajp.20150101.12
© Science Publishing Group